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Changes in the medication methods

When Göran Sedvall, Fritz Axel Wiesel and Henrik Nybäck in the mid-seventies came to the psychiatric clinic at the Karolinska Hospital, big substantial changes could be observed. The research about psychoses that was then initiated was characterized by the wish to try to understand the contributing factors behind mental illness. There was also a clinical direction that was focused on the question how the drugs could be improved,” says Håkan. “It was a matter of first investigating what the optimal dose was and when the treatment should be initiated, then the treatment began, and finally the effects were observed. Prior to this point, it was rather a matter of starting with the highest possible dose.”

“The problem was also that people, probably because of the current attitude in society, not seeed for help before they were practically collapsing from the disease. And at this acute stage people often did not quite receive the right kind of treatment.” Håkan says the praxis at this time was to start with a relatively high dose from the beginning, which usually caused serious side effects. From there the dose was successively decreased until a minimal amount of side effects could be observed.

Today, the procedure is reversed, that is one starts with a low dose and then increases it until the symptoms start disappearing. Håkan here points out that studies later showed that the new way of medicating for that matter did not lead to longer periods of treatment. Modern techniques have also shown that the clinical dose in fact does not have to be as high as it was first thought.

Håkan further says that the new routines in psychiatric health care aimed to make the patient fells as involved as possible. It was important to keep contact with the home, the family, and the patient’s social network. The nursing staff often went on day trips or arranged other activities. Basically, the patient was supposed to feel welcomed and part of the group.

“One negative thing that was negative though,” means Håkan, “was that there in many cases was a wrongful opinion that the patient was ill because of the way he or she had been treated. And in this way, patients and other people that were close to the patient were often easily blamed for more that they were guilty of.”

 

 

 

 

 

 

 

 


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© HUBIN updated March 15, 2003 .

Håkan Hall and Ulrika Kahl at Human Brain Informatics
Department of Clinical Neuroscience, Psychiatry Section
Karolinska Institutet, SE-171 76 Stockholm, SWEDEN.
Phone: +46-8-517 75651 Fax: +46-8-34 65 63 E-mail: info@hubin.org