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Medication news 2003


American researchers seek approval for drug implant (10/06/03)


Zyprexa gets warning label (09/23/03)
FDA approves new supplement for treatment of schizophrenic patients (09/17/03)
Orally administered olanzapine may be used to treat agitated schizophrenia patients (09/09/03)


New evidence that new antispychotic medications can increase the risk for diabetes (08/28/03)
More and more children on antipsychotic medications (08/15/03)


Schizophrenia drugs linked to diabetes (06/05/03)


And the debate goes on... (05/23/03)
Are newer antipsychotic drugs better than the older ones? (05/13/03)
Fast-dissolving form of Risperdal released (05/13/03)


American researchers seek approval for drug implant (10/06/03)
Researchers in the US are about to seek FDA approval of a surgically implanted tablet that could deliver daily doses of psychiatric medication for as long as a year. The implant is biodegradable and about 1 centimeter in diameter and 1 millimeter thick. The implant, which could contain antidepressants as well as other medications, gradually disappears over the course of a year, slowly releasing the drug. If the patient has to be taken off the drug, the effects immediately cease when the tablet is removed.
Source: The Boston Globe, Friday, September 26, 2003
Read more in article at www.boston.com

Zyprexa gets warning label (09/23/03)
Because of indications from a number of studies, that several new antipsychotic medications are associated with an increased risk for diabetes, pharmaceutical company Eli Lilly and Co. now have to post a warning of a diabetes risk on its best-selling drug Zyprexa.
Source: Indystar.com, Tuesday, September 18, 2003
Read more in article at www.indystar.com

FDA approves new supplement for treatment of schizophrenic patients (09/17/03)
The US Food and Drug Administration (FDA) has approved a Supplemental New Drug Application (sNDA) for Abilify™ (aripiprazole) for treatment of patients with schizophrenia.
Source: Doctor's Guide, Tuesday, September 9, 2003

Read more in article at www.docguide.com

Orally administered olanzapine may be used to treat agitated schizophrenia patients (09/09/03)
Olanzapine is anantipsychotic medication that is often used to treat schizophrenia and bipolar disorder. Agitated patients are usually treated with a typical antipsychotic drug such as haloperidol, which is then replaced with olanzapine or another atypical antipsychotic after the acute stabilisation phase. Now researchers have found that a rapid initial high dose of oral olanzapine may be useful in treating agitated schizophrenics or patients with bipolar disorder.
Source: Doctor's Guide, Friday, August 29, 2003

Read more in article at www.docguide.com

New evidence that new antispychotic medications can increase the risk for diabetes (08/28/03)
Previous research has shown that newer antipsychotic medications may increase the risk for diabetes. Now an American study supports these indications, showing that three commonly used drugs, Eli Lilly’s Zyprexa, Jannsen Pharmaceutica’s Risperdal, and Astra Zeneca’s Seroquel, are all associated with a higher rates of diabetes in the patients than older drugs like Haldol.
Source: New York Times, Monday, August 25, 2003

Read more in article at www.nytimes.com

More and more children on antipsychotic medications (08/15/03)
The development of better diagnosis methods have led to the possibility of diagnosing psychiatric diseases at an earlier age. This, in turn, means doctors are prescribing antipsychotic medications to more and more children.
Source: Seattle Times, Wednesday, August 13, 2003

Läs mer i artikel på www.seattletimes.nwsource.com

Schizophrenia drugs linked to diabetes (06/05/03)
Research shows that newer antipsychotics can elevate blood sugar levels, which may lead to diabetes. Of the 121 people with schizophrenia that were investigated in a study at Yale, almost 25% developed high blood sugar levels while taking Clozaril.
Source: WebMD, Tuesday, June 3, 2003

Read more in article at www.webmd.com

And the debate goes on... (05/23/03)
How superior are the new antipsychotics? And balancing side effects and cost, are they really that much advantageous than older antispychotic medications? An extensive article in NY Times discusses the issue.
Source: NY Times, Friday, May 23, 2003

Read more in article at www.nytimes.com
Fulltext article in PDF format

Are newer antipsychotic drugs better than the older ones? (05/13/03)
Newer antipsychotics are considered to be superior to older antispychotic drugs - more efficient and with fewer side effects. Now current reports say this may not be completely true.
Source: BBC News and WebMD, Thursday, May 8-9, 2003

Read more in article at www.bbc.co.uk
Read more in article at www.webmd.com

Fast-dissolving form of Risperdal released (05/13/03)
Risperdal® (risperidone), marketed by Janssen Pharmaceutica Products, L.P., is the most widely prescribed antipsychotic medication in the US. Now the drug is released as a fast-dissolving form of schizophrenia medication, Risperdal M-TAB™, which dissolves in seconds when placed on the tongue.
Source: Doctor's Guide, Tuesday, May 6, 2003
Read more in articel at www.docnews.com


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Håkan Hall and Ulrika Kahl at Human Brain Informatics
Department of Clinical Neuroscience, Psychiatry Section
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