To test whether it would be possible to feed
different research data into a database and then see a correlation,
a small, local database was built at IBM. Into this, previous genetic
and biochemical research data were inserted, and a new statistical
methodology, “data mining”, was applied on them. The result
was, among others, that from this small material, a correlation
was found between anxiety and a certain type of dopamine D2 receptors.
This correlation was documented and can be found in HUBIN’s
first activity plan, which is dated 12/03/97. A week later, December
10, 1997, a totally  independent
research team presented results concerning the exact same correlation
between anxiety and dopamine receptors. The way of working with
a database and data mining, which is the primary idea of the HUBIN
project, was hence shown to be possible.
Today, HUBIN is on its fifth year. The purpose
of the project is to accelerate research and development in order
to gather new knowledge and novel treatment methods for human brain
disease. To the research that goes on belong a number of projects,
where for instance the anatomy and physiology of the brain, genetics,
and assessments of psychological symptoms and personality in schizophrenia
are studied. Into the database, the respective results from the
different projects are fed in a standardized way, and analyzed with
recently developed statistical methods. The hope is to get an answer
to how symptoms, genetics, anatomy, and so forth are related to
each other and what importance they have for the development of
schizophrenia.
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