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Seizures

seziureIn a small number of people, antipsychotic medication can lead to seizures. A seizure is a disturbances of brain function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. When a patient has a seizure, he or she manifests "abnormal motor, sensory and psychic phenomena". For example, the patient may get severe convulsions.

Use of antipsychotic medication can lower a person´s threshold for seizures, i.e. they happen more easily. The frequency of seizures is dose-related, with higher doses related to greater risks.

In particular, treatment with the atypic antipsychotic clozapine may lead to a greater risk of seizures. Sometimes the doctor chooses to combine antipsychotics with anticonvulsant medications to cope with, and control, the seizure problems.

 

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© HUBIN updated September 26, 2002 .

Håkan Hall and Ulrika Kahl at Human Brain Informatics
Department of Clinical Neuroscience, Psychiatry Section
Karolinska Institutet, SE-171 76 Stockholm, SWEDEN.
Phone: +46-8-517 75651 Fax: +46-8-34 65 63 E-mail: info@hubin.org